Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007701 | 0.83 | CTRC (0.41) | CYP1A2POLBNAMPTMAPTADORA3 | |
| SCHEMBL4010263 | 0.82 | DHPS (0.41) | CYP1A2POLBNAMPTMAPTCNR1 | |
| SCHEMBL4008512 | 0.81 | MAPT (0.42) | CYP1A2POLBMAPTDHPSADORA3 | |
| SCHEMBL4006533 | 0.80 | PDE4B (0.39) | CYP1A2POLBNAMPTMAPTDHPS | |
| SCHEMBL4014827 | 0.78 | NAMPT (0.37) | CYP1A2POLBNAMPTMAPTDHPS | |
| SCHEMBL4015692 | 0.76 | DHPS (0.40) | CYP1A2POLBNAMPTMAPTCNR1 | |
| SCHEMBL8027468 | 0.75 | DHODH (0.41) | CYP1A2POLBNAMPTMAPTDHPS | |
| SCHEMBL4008889 | 0.75 | DHPS (0.41) | CYP1A2POLBMAPTDHPSADORA3 | |
| SCHEMBL4009408 | 0.73 | DHPS (0.39) | CYP1A2POLBNAMPTMAPTCNR1 | |
| SCHEMBL4009395 | 0.73 | CNR1 (0.41) | NAMPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |