Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015692 | 0.88 | DHPS (0.40) | ATMNAMPTCTRCADORA3DHPS | |
| SCHEMBL4007716 | 0.85 | ADORA3 (0.39) | NAMPTADORA3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8031508 | 0.83 | ATM (0.46) | ATMNAMPTCTRCADORA3SMN1; SMN2 | |
| SCHEMBL4009344 | 0.81 | NPSR1 (0.39) | NAMPTADORA3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8031087 | 0.81 | ATM (0.51) | ATMNAMPTCTRCSMN1; SMN2MEN1 | |
| SCHEMBL4014816 | 0.79 | ATM (0.45) | ATMNAMPTADORA3DHPSSMN1; SMN2 | |
| SCHEMBL4010260 | 0.75 | ATM (0.45) | ATMADORA3SMN1; SMN2LMNARAB9A | |
| SCHEMBL4007862 | 0.74 | NAMPT (0.38) | ATMNAMPTCTRCADORA3SMN1; SMN2 | |
| SCHEMBL4009395 | 0.74 | CNR1 (0.41) | NAMPTCNR1 | |
| SCHEMBL4007725 | 0.74 | ADORA3 (0.39) | NAMPTADORA3SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |