Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007716 | 0.84 | ADORA3 (0.39) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL8040303 | 0.83 | NPSR1 (0.42) | NPSR1KDM4EHPGDTSHRACP1 | |
| SCHEMBL4010086 | 0.81 | ATM (0.46) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL8047253 | 0.81 | ACP1 (0.43) | NPSR1KDM4EHPGDTSHRACP1 | |
| SCHEMBL4015692 | 0.80 | DHPS (0.40) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL8041741 | 0.75 | NPSR1 (0.42) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL4007862 | 0.74 | NAMPT (0.38) | KDM4ENAMPTMEN1KMT2AADORA3 | |
| SCHEMBL8040669 | 0.73 | NPSR1 (0.42) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL4007725 | 0.73 | ADORA3 (0.39) | NPSR1KDM4EHPGDTSHRNAMPT | |
| SCHEMBL8038367 | 0.72 | SMN1; SMN2 (0.40) | NPSR1KDM4EHPGDTSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |