Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419430 | 0.77 | CTSD (0.40) | HTR2ASLC6A4KCNH2CYP3A4CYP2C19 | |
| SCHEMBL515650 | 0.77 | ALDH1A1 (0.40) | HTR2ASLC6A4KCNH2ADAMTS5 | |
| SCHEMBL414221 | 0.73 | SLC6A4 (0.40) | HTR2ASLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL12806559 | 0.72 | HTR2A (0.50) | HTR2ASLC6A4KCNH2HSP90AA1FFAR1 | |
| SCHEMBL13190314 | 0.70 | HTR2A (0.38) | HTR2ASLC6A4KCNH2CYP3A4CYP2C19 | |
| SCHEMBL404243 | 0.70 | TSHR (0.40) | HTR2A | |
| SCHEMBL419311 | 0.70 | HTR2A (0.36) | HTR2ASLC6A4KCNH2SLC6A3ADAMTS5 | |
| SCHEMBL10196025 | 0.69 | HSP90AA1 (0.41) | HTR2ASLC6A4KCNH2HSP90AA1FFAR1 | |
| SCHEMBL21820786 | 0.68 | HSP90AA1 (0.71) | HTR2ASLC6A4KCNH2HSP90AA1SLC6A2 | |
| SCHEMBL405747 | 0.68 | MAOA (0.35) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-20120021912-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2389066-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021912-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | HTR2A 1320/4885SLC6A4 1443/4885KCNH2 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.