Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742467 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HTR2ASLC6A4KCNH2TAAR1 | |
| SCHEMBL407171 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SLC6A4LMNAMAOAMAOB | |
| SCHEMBL401599 | 0.77 | HTR2A (0.39) | HTR2ASLC6A4KCNH2ADAMTS5 | |
| SCHEMBL407940 | 0.72 | PNLIP (0.39) | ALDH1A1SLC6A4LMNAMAOAMAOB | |
| SCHEMBL419311 | 0.71 | HTR2A (0.36) | ALDH1A1HTR2ASLC6A4KCNH2LMNA | |
| SCHEMBL28659130 | 0.71 | HTR2A (0.50) | ALDH1A1HTR2ASLC6A4KCNH2MAOA | |
| SCHEMBL414221 | 0.70 | SLC6A4 (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL15186258 | 0.69 | HTR2A (0.47) | ALDH1A1HTR2ASLC6A4KCNH2MAOA | |
| SCHEMBL405747 | 0.69 | MAOA (0.35) | ALDH1A1HTR2ASLC6A4KCNH2TAAR1 | |
| SCHEMBL516287 | 0.69 | MAOB (0.36) | ALDH1A1HTR2ASLC6A4KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393769-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-12-10 | — | — | EP | disclosed |
| US-8680339-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-20120028800-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2393769-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089210-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028800-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | ALDH1A1 14/4885HTR2A 1320/4885SLC6A4 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.