SCHEMBL4015993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017619	0.87	HTT (0.45)	MAPTKDM4EPOLBLMNARAB9A
	SCHEMBL4017046	0.85	ALDH1A1 (0.48)	MAPTALDH1A1KDM4EPOLBLMNA
	SCHEMBL4017692	0.85	NPC1 (0.48)	MAPTALDH1A1POLBGAATDP1
	SCHEMBL4018541	0.84	LMNA (0.58)	MAPTALDH1A1KDM4ETDP1LMNA
	SCHEMBL4020276	0.83	LMNA (0.52)	MAPTALDH1A1POLBGAATDP1
	SCHEMBL4018187	0.83	SMN1; SMN2 (0.52)	MAPTALDH1A1LMNARAB9ANPC1
	SCHEMBL4020375	0.80	KDR (0.61)	MAPTKDM4ELMNARAB9ANPC1
	SCHEMBL4021062	0.80	LMNA (0.56)	MAPTALDH1A1POLBGAALMNA
	SCHEMBL4015260	0.79	KDR (0.52)	MAPTLMNARAB9ANPC1HTT
	SCHEMBL4021268	0.79	NAMPT (0.52)	MAPTALDH1A1POLBGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.