SCHEMBL4017619

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017046	0.92	ALDH1A1 (0.48)	HTTLMNACCNCCDK8NAMPT
	SCHEMBL4015993	0.87	MAPT (0.50)	HTTBLMLMNACCNCCDK8
	SCHEMBL4017692	0.85	NPC1 (0.48)	HTTLMNACCNCCDK8KDR
	SCHEMBL4020276	0.83	LMNA (0.52)	HTTLMNAMAPTHPGDSMN1; SMN2
	SCHEMBL4018187	0.83	SMN1; SMN2 (0.52)	HTTLMNAKDRFLT1NAMPT
	SCHEMBL4020375	0.82	KDR (0.61)	HTTLMNAKDRFLT1NAMPT
	SCHEMBL4018122	0.81	SMN1; SMN2 (0.55)	HTTLMNAKDRFLT1NAMPT
	SCHEMBL4018541	0.80	LMNA (0.58)	HTTLMNAKDRFLT1MAPT
	SCHEMBL4015260	0.79	KDR (0.52)	HTTLMNAKDRFLT1NAMPT
	SCHEMBL4021268	0.79	NAMPT (0.52)	HTTLMNAKDRNAMPTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.