SCHEMBL4020276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018187	0.90	SMN1; SMN2 (0.52)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4017046	0.83	ALDH1A1 (0.48)	LMNASMN1; SMN2KMT2ANPC1RAB9A
	SCHEMBL4017692	0.83	NPC1 (0.48)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4015993	0.83	MAPT (0.50)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4017619	0.83	HTT (0.45)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4018541	0.82	LMNA (0.58)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4020375	0.82	KDR (0.61)	LMNAMEN1KMT2ANPC1RAB9A
	SCHEMBL4015260	0.81	KDR (0.52)	LMNASMN1; SMN2NPC1RAB9AHTT
	SCHEMBL4021268	0.81	NAMPT (0.52)	LMNASMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL4018122	0.81	SMN1; SMN2 (0.55)	LMNASMN1; SMN2MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.