Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768445 | 0.70 | ALDH1A1 (0.43) | MAPTSMN1; SMN2LIN28ATDP1LMNA | |
| SCHEMBL13768806 | 0.68 | MAPT (0.62) | MAPTSMN1; SMN2LIN28ATDP1SLC1A5 | |
| SCHEMBL13768698 | 0.67 | ALDH1A1 (0.49) | MAPTSMN1; SMN2LIN28ATDP1SLC1A5 | |
| SCHEMBL12977564 | 0.65 | TDP1 (0.66) | MAPTSMN1; SMN2LIN28ATDP1KDM4E | |
| SCHEMBL4474970 | 0.65 | MAPT (0.59) | MAPTSMN1; SMN2LIN28ATDP1SLC1A5 | |
| SCHEMBL3791451 | 0.64 | ALDH1A1 (0.46) | TDP1TSHR | |
| SCHEMBL13768808 | 0.64 | MAPT (0.64) | MAPTSMN1; SMN2LIN28ATDP1SLC1A5 | |
| SCHEMBL29407086 | 0.63 | MAPT (0.78) | MAPTSMN1; SMN2LIN28ATDP1CXCR4 | |
| SCHEMBL57060 | 0.63 | MAPT (0.78) | MAPTSMN1; SMN2LIN28ATDP1CXCR4 | |
| SCHEMBL231092 | 0.63 | TDP1 (1.00) | MAPTSMN1; SMN2LIN28ATDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |