Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015317 | 0.80 | LMNA (0.60) | ALDH1A1TDP1HTTMAPTLMNA | |
| SCHEMBL4016010 | 0.70 | MAPT (0.40) | TDP1MAPTSMN1; SMN2LMNALIN28A | |
| SCHEMBL13768806 | 0.68 | MAPT (0.62) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL20694123 | 0.68 | ALDH1A1 (0.61) | ALDH1A1HTTMAPTSMN1; SMN2GAA | |
| SCHEMBL28334006 | 0.67 | ALDH1A1 (0.67) | ALDH1A1TDP1HTTMAPTSMN1; SMN2 | |
| SCHEMBL1921484 | 0.67 | MAPT (0.77) | ALDH1A1HTTMAPTSMN1; SMN2GAA | |
| SCHEMBL13768698 | 0.66 | ALDH1A1 (0.49) | ALDH1A1TDP1HTTMAPTSMN1; SMN2 | |
| SCHEMBL7341511 | 0.66 | MAPT (0.58) | ALDH1A1HTTMAPTSMN1; SMN2GAA | |
| SCHEMBL7350113 | 0.65 | YAP1 (0.55) | ALDH1A1HTTMAPTSMN1; SMN2GAA | |
| SCHEMBL7342714 | 0.65 | YAP1 (0.55) | ALDH1A1HTTMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |