Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016843 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL4016837 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL26235654 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL15811059 | 0.77 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL5492983 | 0.76 | NOTUM (0.64) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL28195698 | 0.75 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL4780895 | 0.75 | KMT2A (0.83) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL16220559 | 0.75 | TSHR (0.81) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31222353 | 0.75 | TSHR (0.81) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5006023 | 0.74 | TSHR (0.75) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483492-B | Dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2023-07-21 | — | — | CN | disclosed |