Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013470 | 0.92 | ALDH1A1 (0.54) | RAB9ACCR3OPRM1OPRK1ALDH1A1 | |
| SCHEMBL4016844 | 0.91 | MAPT (0.45) | CCR3KMT2AMAPT | |
| SCHEMBL301931 | 0.82 | CACNA1H (0.40) | RAB9ACCR3CHRM4MAPT | |
| SCHEMBL3565136 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBNAMPT | |
| SCHEMBL3557299 | 0.82 | CCR3 (0.67) | RAB9ACCR3MEN1KMT2APOLB | |
| SCHEMBL3565549 | 0.81 | HTR2A (0.49) | MEN1KMT2APOLBNAMPTMAPT | |
| SCHEMBL3565154 | 0.81 | UTS2R (0.46) | RAB9ACCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL3564763 | 0.80 | NAMPT (0.47) | RAB9ACCR3MEN1KMT2APOLB | |
| SCHEMBL3557010 | 0.80 | CARM1 (0.52) | RAB9AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3559283 | 0.76 | RAB9A (0.44) | RAB9ACCR3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670470-B1 | PYRIDINE DERIVATIVES AND USE THEREOF AS UROTENSIN II ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-04-08 | — | — | EP | claimed |