SCHEMBL4018031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4023357	0.85	MEN1 (0.50)	KDRFLT1MEN1KMT2ANPC1
	SCHEMBL4022408	0.85	KDR (0.61)	KDRFLT1NAMPTMEN1KMT2A
	SCHEMBL4015949	0.82	ALDH1A1 (0.56)	KDRNAMPTMEN1KMT2ANPC1
	SCHEMBL4015716	0.82	NPC1 (0.47)	KDRFLT1MAPK14NAMPTMEN1
	SCHEMBL4018844	0.81	MAPT (0.55)	KDRFLT1MEN1KMT2ANPC1
	SCHEMBL4028520	0.81	NAMPT (0.54)	KDRFLT1NAMPTNPC1RAB9A
	SCHEMBL4017059	0.79	BLM (0.50)	KDRFLT1NAMPTMEN1KMT2A
	SCHEMBL4024443	0.79	ALDH1A1 (0.46)	KDRFLT1MEN1KMT2ANPC1
	SCHEMBL4020868	0.79	MAPT (0.50)	KDRFLT1NAMPTMEN1KMT2A
	SCHEMBL4019394	0.79	TP53 (0.43)	KDRFLT1NAMPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.