SCHEMBL4020868

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017059	0.87	BLM (0.50)	MAPTALDH1A1BLMNPC1RAB9A
	SCHEMBL4024443	0.85	ALDH1A1 (0.46)	MAPTALDH1A1KDM4EPOLBGAA
	SCHEMBL4019394	0.85	TP53 (0.43)	MAPTALDH1A1POLBBLMNPC1
	SCHEMBL4023357	0.84	MEN1 (0.50)	MAPTALDH1A1POLBTDP1BLM
	SCHEMBL4018844	0.83	MAPT (0.55)	MAPTALDH1A1POLBGAATDP1
	SCHEMBL4023440	0.83	ESRRG (0.54)	MAPTNPC1RAB9APKMKMT2A
	SCHEMBL4022408	0.80	KDR (0.61)	MAPTKDM4ENPC1RAB9AKMT2A
	SCHEMBL4015949	0.80	ALDH1A1 (0.56)	MAPTALDH1A1KDM4ETDP1NPC1
	SCHEMBL4018399	0.79	MAPT (0.48)	MAPTALDH1A1KDM4EPOLBGAA
	SCHEMBL4015806	0.79	L3MBTL1 (0.50)	MAPTALDH1A1KDM4EPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.