SCHEMBL4015949

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4028520	0.84	NAMPT (0.54)	TP53NAMPTNPC1SMN1; SMN2KDR
	SCHEMBL4023357	0.83	MEN1 (0.50)	ALDH1A1LMNAKMT2AMEN1NPC1
	SCHEMBL4022408	0.83	KDR (0.61)	LMNAMAPK1NAMPTKMT2AMEN1
	SCHEMBL4018031	0.82	KDR (0.51)	ALDH1A1NAMPTKMT2AMEN1NPC1
	SCHEMBL4018844	0.80	MAPT (0.55)	ALDH1A1LMNATP53KMT2AMEN1
	SCHEMBL4020868	0.80	MAPT (0.50)	ALDH1A1LMNAMAPK1NAMPTKMT2A
	SCHEMBL4015775	0.79	ALDH1A1 (0.54)	ALDH1A1LMNATP53MAPK1NAMPT
	SCHEMBL4017521	0.79	FADS1 (0.43)	TP53SMN1; SMN2KDRMAPT
	SCHEMBL4018400	0.78	KDR (0.71)	ALDH1A1LMNATP53MAPK1NAMPT
	SCHEMBL4015716	0.78	NPC1 (0.47)	ALDH1A1LMNAMAPK1NAMPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.