SCHEMBL4018844

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4023440	0.90	ESRRG (0.54)	MAPTSMN1; SMN2MEN1KMT2ARAB9A
	SCHEMBL4017059	0.83	BLM (0.50)	MAPTSMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4020868	0.83	MAPT (0.50)	MAPTSMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4019394	0.83	TP53 (0.43)	MAPTSMN1; SMN2MEN1KMT2ARAB9A
	SCHEMBL4024443	0.83	ALDH1A1 (0.46)	MAPTSMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4023357	0.82	MEN1 (0.50)	MAPTSMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4022408	0.82	KDR (0.61)	MAPTLMNAMEN1KMT2ARAB9A
	SCHEMBL4018031	0.81	KDR (0.51)	SMN1; SMN2MEN1KMT2ARAB9ANPC1
	SCHEMBL4020470	0.81	SMN1; SMN2 (0.55)	MAPTSMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL4017521	0.80	FADS1 (0.43)	MAPTSMN1; SMN2KDRESRRGFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.