Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779990 | 0.89 | L3MBTL1 (0.55) | KMT2AMEN1L3MBTL1TSHRHSD17B10 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.80 | TSHR (0.68) | KMT2ATSHRHSD17B10MAPTFAAH | |
| SCHEMBL776229 | 0.79 | MAPT (0.61) | KMT2AL3MBTL1TSHRHSD17B10MAPT | |
| SCHEMBL28293647 | 0.79 | TSHR (0.62) | KMT2ATSHRHSD17B10MAPTFAAH | |
| SCHEMBL23657904 | 0.79 | MLNR (0.53) | KMT2AMEN1L3MBTL1TAS2R14ALDH1A1 | |
| SCHEMBL30833518 | 0.79 | MEN1 (0.46) | KMT2AMEN1L3MBTL1GBA1PGR | |
| SCHEMBL17942342 | 0.79 | MEN1 (0.46) | KMT2AMEN1L3MBTL1GBA1PGR | |
| SCHEMBL19707186 | 0.79 | MMP2 (0.55) | TSHRHSD17B10MAPTFAAHPRSS1 | |
| SCHEMBL4205946 | 0.79 | TSHR (0.53) | TSHRHSD17B10MAPTFAAHPRSS1 | |
| SCHEMBL10181269 | 0.79 | LOXL2 (0.49) | KMT2AMEN1L3MBTL1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |