Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025022 | 0.89 | TSHR (0.49) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1856043 | 0.86 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4711874 | 0.86 | SMN1; SMN2 (0.53) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1852234 | 0.84 | HTT (0.51) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4019037 | 0.84 | HTT (0.51) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1853649 | 0.81 | ALDH1A1 (0.46) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4715407 | 0.77 | SMN1; SMN2 (0.69) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4714650 | 0.76 | MEN1 (0.47) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL4717989 | 0.76 | MEN1 (0.47) | HTTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1853154 | 0.75 | KMT2A (0.66) | HTTSMN1; SMN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | LABORATOIRES SERONO SA (CH) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | STS, TST, SULT1A1 | HTT 4318/4885SMN1; SMN2 2147/4885MEN1 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.