SCHEMBL4019838

SCHEMBL4019838

CCC[Ge](CCC)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 9/20 0.47
▸ CES2 O00748 8/20 0.47
▸ LMNA P02545 1/20 0.46
▸ TSHR P16473 3/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ POLB P06746 1/20 0.43
▸ PARP1 P09874 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ PMP22 Q01453 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ HPGD P15428 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4011711 0.88 CES2 (0.50) CES1CES2LMNATSHRCYP3A4
SCHEMBL274249 0.83 CES1 (0.48) CES1CES2LMNATSHRCYP3A4
Bromomethane SCHEMBL30082988 0.79 CES1 (0.45) CES1CES2LMNATSHRCYP3A4
SCHEMBL4953798 0.77 CES2 (0.47) CES1CES2LMNAPTGS2ALDH1A1
SCHEMBL4019209 0.74 CES1 (0.48) CES1CES2LMNATSHRCYP3A4
SCHEMBL22204644 0.74 CES1 (0.48) CES1CES2LMNATSHRCYP3A4
SCHEMBL272138 0.72 TDP1 (0.55) CES1CES2LMNATSHRCYP3A4
SCHEMBL1632835 0.72 TDP1 (0.55) CES1CES2LMNATSHRCYP3A4
Benzamide SCHEMBL2401802 0.71 PARP1 (0.76) CES1CES2LMNATSHRCYP3A4
Benzophenone SCHEMBL11693944 0.70 ALDH1A1 (0.74) CES1CES2LMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646733-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-12 — — EP claimed
US-20240248400-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-07-25 — — US claimed
WO-2024147917-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-07-11 — — WO claimed
EP-4646733-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-12 — — EP disclosed
WO-2025128307-A1 POLYIMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 — — WO disclosed
US-20250188223-A1 POLYIMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 — — US disclosed
US-20250046717-A1 Microelectronic Devices with Good Reliability and Related Compositions and Methods FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2025-02-06 — — US disclosed
WO-2025029552-A2 MICROELECTRONIC DEVICES WITH GOOD RELIABILITY AND RELATED COMPOSITIONS AND METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-02-06 — — WO disclosed
US-20240248400-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-07-25 — — US disclosed
WO-2024147917-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-07-11 — — WO disclosed
US-7605190-B2 Polymerizable compositions with acylgermanium compounds IVOCLAR VIVADENT AG (LI) 2009-10-20 — — US disclosed
EP-1905415-B1 Polymerisable compositions comprising acyl-germanium as initiators IVOCLAR VIVADENT AG (LI) 2009-07-01 — — EP disclosed
US-20080277814-A1 Polymerizable compositions with acylgermanium compounds IVOCLAR VIVADENT AG (LI) 2008-11-13 — — US disclosed
EP-1905415-A1 Polymerisable compositions comprising acyl-germanium as initiators IVOCLAR AG (LI) 2008-04-02 — — EP disclosed
EP-1905413-A1 Polymerisable compositions comprising acyl-germanium as initiators Ivoclar Vivadent AG (LI) 2008-04-02 — — EP disclosed
US-20080076847-A1 Polymerizable compositions with acylgermanes as initiatiors IVOCLAR VIVADENT AG (LI) 2008-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076847-A1 Polymerizable compositions with acylgermanes as initiatiors NR1I3, NR4A1, NR1I2 CES1 548/4885CES2 1371/4885LMNA 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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