Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019838 | 0.88 | CES1 (0.47) | CES2CES1PTGS2NAAALMNA | |
| SCHEMBL4953798 | 0.81 | CES2 (0.47) | CES2CES1PTGS2NAAALMNA | |
| SCHEMBL274249 | 0.79 | CES1 (0.48) | CES2CES1LMNAALDH1A1POLB | |
| Bromomethane SCHEMBL30082988 | 0.76 | CES1 (0.45) | CES2CES1LMNAALDH1A1POLB | |
| Benzamide SCHEMBL28124928 | 0.74 | CYP3A4 (0.70) | CES2CES1NAAALMNAPOLB | |
| Benzamide SCHEMBL22117133 | 0.74 | CYP3A4 (0.70) | CES2CES1PTGS2NAAALMNA | |
| Benzophenone SCHEMBL23014697 | 0.73 | ALDH1A1 (0.67) | CES2CES1NAAALMNAALDH1A1 | |
| Benzoic Acid SCHEMBL28845500 | 0.73 | TSHR (0.67) | CES2CES1NAAAALDH1A1MAPT | |
| Benzoic Acid SCHEMBL6573567 | 0.73 | TSHR (0.67) | CES2CES1NAAAALDH1A1TSHR | |
| Benzoic Acid SCHEMBL9157936 | 0.73 | TSHR (0.67) | CES2CES1NAAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119377-B1 | PHOTOPOLYMERISABLE AND DUAL HARDENING DENTAL MATERIAL BASED ON THIOUREA DERIVATIVES AND BISACYLDIALKYLGERMANIUM-COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2021-12-29 | — | — | EP | claimed |
| CN-106132380-B | Photopolymerizable dual-cure dental materials based on thiourea derivatives | 义获嘉伟瓦登特公司 | 2020-02-11 | — | — | CN | claimed |
| EP-2921156-B1 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2019-10-02 | — | — | EP | claimed |
| US-10195121-B2 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2019-02-05 | — | — | US | claimed |
| US-10130562-B2 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2018-11-20 | — | — | US | claimed |
| US-20170143592-A1 | MONOMER MIXTURE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2017-05-25 | — | — | US | claimed |
| US-20170128328-A1 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2017-05-11 | — | — | US | claimed |
| EP-2921154-B1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | IVOCLAR VIVADENT AG (LI) | 2017-03-08 | — | — | EP | claimed |
| EP-3119377-A1 | PHOTOPOLYMERISABLE AND DUAL CURING DENTAL MATERIALS BASED ON THIOUREA DERIVATIVES | Ivoclar Vivadent AG (LI) | 2017-01-25 | — | — | EP | claimed |
| WO-2015139811-A1 | MONOMER MIXTURES FOR PRODUCING DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2015-09-24 | — | — | WO | claimed |
| WO-2015140276-A1 | PHOTOPOLYMERISABLE AND DUAL CURING DENTAL MATERIALS BASED ON THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2015-09-24 | — | — | WO | claimed |
| EP-2921156-A1 | Monomer mixture for the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| EP-2921154-A1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| EP-4717249-A1 | DENTAL COMPOSITION | Shofu Inc. (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20260083642-A1 | DENTAL COMPOSITION | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | SHOFU INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| US-20080277814-A1 | Polymerizable compositions with acylgermanium compounds | IVOCLAR VIVADENT AG (LI) | 2008-11-13 | — | — | US | disclosed |
| EP-1905413-A1 | Polymerisable compositions comprising acyl-germanium as initiators | Ivoclar Vivadent AG (LI) | 2008-04-02 | — | — | EP | disclosed |
| EP-1905415-A1 | Polymerisable compositions comprising acyl-germanium as initiators | IVOCLAR AG (LI) | 2008-04-02 | — | — | EP | disclosed |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | IVOCLAR VIVADENT AG (LI) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | BOLA2; BOLA2B, LBR, COL2A1 | CES2 578/4885CES1 451/4885PTGS2 799/4885 |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | NR1I3, NR4A1, NR1I2 | CES2 1371/4885CES1 548/4885PTGS2 1703/4885 |
| US-20260083642-A1 | DENTAL COMPOSITION | TAS2R42, COL2A1, TAS2R1 | CES2 416/4885CES1 1600/4885PTGS2 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.