Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729895 | 0.88 | LOXL2 (0.48) | TPSAB1PRSS1TPSD1TPSG1PLG | |
| SCHEMBL2173527 | 0.87 | MEN1 (0.43) | TPSAB1PRSS1TPSD1TPSG1PLG | |
| SCHEMBL27571682 | 0.86 | TSHR (0.51) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL28861927 | 0.85 | NPC1 (0.51) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27811154 | 0.85 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27832835 | 0.84 | LOXL2 (0.44) | TPSAB1PRSS1TPSD1TPSG1PLG | |
| SCHEMBL27805750 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27848344 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL28861926 | 0.83 | MAPT (0.56) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27729183 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121396-A1 | TRICYCLIC COMPOUND THAT ACTS AS PLASMA KALLIKREIN INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2021-06-24 | — | — | WO | disclosed |
| CN-108770357-A | Polymer combined vaccine | 芝加哥大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-108350062-A | Targeting proteins are degraded to weaken the relevant bad inflammatory reaction of adoptive T cell therapy | 达纳-法伯癌症研究所股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107257800-A | Method for inducing target protein degradation by bifunctional molecules | 达纳-法伯癌症研究所股份有限公司 | 2017-10-17 | — | — | CN | disclosed |
| CN-101528680-A | New phenylsulfamoyl benzamide derivatives as bradykinin antagonists | RICHTER GEDEON NYRT (HU) | 2009-09-09 | — | — | CN | disclosed |
| US-7482487-B2 | Phenylaminoethanol derivatives as β2 receptor agonists | PFIZER INC (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070264262-A1 | Phenylaminoethanol Derivates as Beta 2 Receptor Agonists | BROWN ALAN D | 2007-11-15 | — | — | US | disclosed |
| EP-1577292-A1 | Phenylaminoethanol derivatives as beta2 receptor agonists | Pfizer Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070264262-A1 | Phenylaminoethanol Derivates as Beta 2 Receptor Agonists | ADRB2, ADRB1, ADRA2C | TPSAB1 35/4885PRSS1 2379/4885TPSD1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.