Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350992 | 0.80 | NR1H4 (0.42) | HTTS1PR1S1PR5SMN1; SMN2ALDH1A1 | |
| SCHEMBL29822795 | 0.74 | MAPT (0.37) | HTTSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL29079983 | 0.74 | NPC1 (0.39) | HTTSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9108668 | 0.70 | KMT2A (0.51) | TSHRALDH1A1NPSR1TDP1POLB | |
| SCHEMBL1366894 | 0.70 | ALDH1A1 (0.55) | HTTSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9108663 | 0.70 | KMT2A (0.51) | TSHRALDH1A1NPSR1TDP1POLB | |
| SCHEMBL16784692 | 0.70 | MAPT (0.46) | HTTSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20027946 | 0.69 | FFAR1 (0.44) | FFAR1SMN1; SMN2TSHRMAPK1ALDH1A1 | |
| SCHEMBL19801268 | 0.68 | NOTUM (0.73) | NOTUM | |
| SCHEMBL18101806 | 0.68 | NOTUM (0.73) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096907-A1 | AZIRIDINE SYNTHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-08-06 | — | — | WO | disclosed |