Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079994 | 0.92 | LMNA (0.43) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL29080004 | 0.92 | ALDH1A1 (0.39) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29079982 | 0.92 | ACHE (0.39) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29079983 | 0.92 | NPC1 (0.39) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29080008 | 0.89 | LMNA (0.44) | MAPTLMNAL3MBTL1GFERALDH1A1 | |
| SCHEMBL29822631 | 0.88 | GRIK2 (0.36) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29079995 | 0.88 | GRIK2 (0.36) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29079997 | 0.79 | LMNA (0.40) | MAPTLMNATDP1NPSR1L3MBTL1 | |
| SCHEMBL29079988 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4020050 | 0.74 | HTT (0.45) | MAPTLMNATDP1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853664-B | Method for synthesizing alpha, beta-unsaturated cyclohexyl ketone compound under palladium catalysis condition | 河南大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-114853664-A | Method for synthesizing alpha, beta-unsaturated heterocyclic hexyl ketone compound under palladium catalysis condition | 河南大学 | 2022-08-05 | — | — | CN | disclosed |