Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890669 | 1.00 | CES2 (0.50) | CES2PTPN5METAP2PDE2ATSHR | |
| SCHEMBL7630799 | 0.81 | CES2 (0.50) | CES2PTPN5TSHRMAPK1ALDH1A1 | |
| SCHEMBL7863217 | 0.80 | PTPN5 (0.41) | CES2PTPN5METAP2TSHRMAPK1 | |
| SCHEMBL3842171 | 0.78 | GLA (0.33) | CES2TSHRKIF11 | |
| SCHEMBL6061078 | 0.77 | CES2 (0.56) | CES2PTPN5PDE2ATSHRMAPK1 | |
| SCHEMBL18313286 | 0.76 | IDO1 (0.41) | CES2TSHRKIF11 | |
| SCHEMBL319516 | 0.76 | IDO1 (0.44) | CES2PTPN5PDE2ATSHRMAPK1 | |
| SCHEMBL31348270 | 0.76 | IDO1 (0.44) | CES2PTPN5PDE2ATSHRMAPK1 | |
| SCHEMBL31371267 | 0.76 | PTPN5 (0.39) | CES2PTPN5METAP2TSHRMAPK1 | |
| SCHEMBL12115135 | 0.74 | PTPN5 (0.38) | CES2PTPN5METAP2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059692-A1 | Process for the preparation of 17beta-N-[2,5-bis(trifluoromethyl)phenyl] carbamoyl-4-aza-5-alpha-androst-1-en-3-one | DR. REDDY'S LABORATORIES LIMITED | 2005-03-17 | — | — | US | claimed |
| US-4079090-A | Preparation of trichloromethyl-trifluoro methyl-benzenes | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | claimed |
| EP-3681928-B1 | PROCESS OF MANUFACTURING POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2023147244-A1 | POLYURETHANE ADHESIVE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-08-03 | — | — | WO | disclosed |
| US-11376241-B2 | Aryl hydrocarbon receptor (AhR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2022-07-05 | — | — | US | disclosed |
| WO-2022086946-A1 | POLYURETHANE COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| EP-3681932-B1 | LEWIS ACID POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-06-09 | — | — | EP | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| EP-3577115-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019055734-A1 | PROCESS OF MANUFACTURING POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| US-20070173523-A1 | Process for the preparation of 17-N-substituted-carbamoyl-4-aza-androst-1-en-3-ones | APOTEX PHARMACHEM INC. (CA) | 2007-07-26 | — | — | US | disclosed |
| US-20050059692-A1 | Process for the preparation of 17beta-N-[2,5-bis(trifluoromethyl)phenyl] carbamoyl-4-aza-5-alpha-androst-1-en-3-one | DR. REDDY'S LABORATORIES LIMITED | 2005-03-17 | — | — | US | disclosed |
| US-20020042541-A1 | Process for producing bis( trifluoromethyl)benzaldehyde | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-04-11 | — | — | US | disclosed |
| US-6326517-B1 | REACTIN AN AROMATIC COMPOUND WITH CARBON MONOXIDE AND AMMONIA | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-12-04 | — | — | US | disclosed |
| US-6268527-B1 | REACTING TRIFLUOROMETHYL SUBSTITUTED AROMATIC COMPOUND WITH CARBON MONOXIDE AND HYDROXY COMPOUND IN PRESENCE OF METAL COMPOUND AND PHOSPHINE DERIVATIVE TO PRODUCE TRIFLUOROMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVE | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0383621-B1 | Diphenyldiacetylene derivative | TODA KOGYO CORP (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5196586-A | Polydiphenyldiacetylenes | TODA KOGYO CORP. (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0383621-A1 | Diphenyldiacetylene derivative | TODA KOGYO CORP. (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4079090-A | Preparation of trichloromethyl-trifluoro methyl-benzenes | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173523-A1 | Process for the preparation of 17-N-substituted-carbamoyl-4-aza-androst-1-en-3-ones | CYP17A1, CYP19A1, NR5A1 | CES2 1262/4885PTPN5 2877/4885METAP2 4335/4885 |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | AHR, ARNT, NR1H2 | CES2 2258/4885PTPN5 1190/4885METAP2 1253/4885 |
| US-20020042541-A1 | Process for producing bis( trifluoromethyl)benzaldehyde | BRPF1, PFAS, FLI1 | CES2 1070/4885PTPN5 1516/4885METAP2 1804/4885 |
| US-11376241-B2 | Aryl hydrocarbon receptor (AhR) modulator compounds | AHR, ARNT, NR1H2 | CES2 2258/4885PTPN5 1190/4885METAP2 1253/4885 |
| US-20050059692-A1 | Process for the preparation of 17beta-N-[2,5-bis(trifluoromethyl)phenyl] carbamoyl-4-aza-5-alpha-androst-1-en-3-one | NR5A1, CYP17A1, CYP19A1 | CES2 861/4885PTPN5 1433/4885METAP2 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.