Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012253 | 0.82 | FAAH (0.68) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4015901 | 0.78 | FAAH (0.67) | FAAHMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL3941492 | 0.78 | FAAH (0.59) | FAAHMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL4011606 | 0.78 | FAAH (0.67) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4012448 | 0.78 | FAAH (0.57) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4013550 | 0.77 | FAAH (0.61) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4013486 | 0.76 | FAAH (0.60) | FAAHMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL4015735 | 0.76 | FAAH (0.61) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4010011 | 0.75 | FAAH (0.59) | FAAHSMN1; SMN2NPC1KDM4EHSD17B10 | |
| SCHEMBL4009176 | 0.75 | FAAH (0.77) | FAAHMAPTNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |