SCHEMBL4020409

SCHEMBL4020409

Cc1cc(C)c(C(=O)C(C[GeH3])(C(=O)c2c(C)cc(C)cc2C)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ LMNA P02545 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ HPGD P15428 2/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.36
▸ MAPT P10636 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ TAS1R3 Q7RTX0 3/20 0.35
▸ TAS1R1 Q7RTX1 3/20 0.35
▸ TAS1R2 Q8TE23 3/20 0.35
▸ GAA P10253 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ MCOLN3 Q8TDD5 1/20 0.34
▸ POLB P06746 1/20 0.33
▸ RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4020406 0.80 L3MBTL1 (0.41) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL13543176 0.74 KDM4E (0.46) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL25805224 0.72 KDM4E (0.44) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL11213326 0.72 KDM4E (0.41) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL7244784 0.72 LMNA (0.41) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL4020410 0.72 ALDH1A1 (0.40) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL11214046 0.71 L3MBTL1 (0.43) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL15824462 0.69 KDM4E (0.42) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL27595773 0.69 L3MBTL1 (0.42) L3MBTL1KDM4ELMNAKMT2AMEN1
SCHEMBL28225713 0.69 TAS1R3 (0.41) L3MBTL1KDM4ELMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240248400-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-07-25 — — US claimed
WO-2024147917-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-07-11 — — WO claimed
EP-4646733-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-12 — — EP disclosed
WO-2025128307-A1 POLYIMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 — — WO disclosed
US-20250188223-A1 POLYIMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 — — US disclosed
US-20250046717-A1 Microelectronic Devices with Good Reliability and Related Compositions and Methods FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2025-02-06 — — US disclosed
WO-2025029552-A2 MICROELECTRONIC DEVICES WITH GOOD RELIABILITY AND RELATED COMPOSITIONS AND METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-02-06 — — WO disclosed
US-20240248400-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2024-07-25 — — US disclosed
WO-2024147917-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-07-11 — — WO disclosed
US-7605190-B2 Polymerizable compositions with acylgermanium compounds IVOCLAR VIVADENT AG (LI) 2009-10-20 — — US disclosed
EP-1905415-B1 Polymerisable compositions comprising acyl-germanium as initiators IVOCLAR VIVADENT AG (LI) 2009-07-01 — — EP disclosed
US-20080277814-A1 Polymerizable compositions with acylgermanium compounds IVOCLAR VIVADENT AG (LI) 2008-11-13 — — US disclosed
EP-1905415-A1 Polymerisable compositions comprising acyl-germanium as initiators IVOCLAR AG (LI) 2008-04-02 — — EP disclosed
EP-1905413-A1 Polymerisable compositions comprising acyl-germanium as initiators Ivoclar Vivadent AG (LI) 2008-04-02 — — EP disclosed
US-20080076847-A1 Polymerizable compositions with acylgermanes as initiatiors IVOCLAR VIVADENT AG (LI) 2008-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076847-A1 Polymerizable compositions with acylgermanes as initiatiors NR1I3, NR4A1, NR1I2 L3MBTL1 2478/4885KDM4E 1099/4885LMNA 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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