Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020786 | 1.00 | LTB4R (0.57) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL10180177 | 0.87 | LTB4R (0.50) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL4017346 | 0.84 | NPC1 (0.65) | KMT2ANPC1RAB9AALDH1A1CA12 | |
| SCHEMBL29786680 | 0.84 | LTB4R (0.61) | LTB4RLTB4R2NPC1ALDH1A1 | |
| SCHEMBL5713225 | 0.83 | LTB4R (0.45) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL30764064 | 0.83 | KMT2A (0.54) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL10147291 | 0.83 | SIGMAR1 (0.47) | LTB4RLTB4R2KMT2ATAAR1MLYCD | |
| SCHEMBL10796032 | 0.81 | TAAR1 (0.50) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| SCHEMBL1520363 | 0.78 | KMT2A (0.59) | LTB4RLTB4R2KMT2ANPC1RAB9A | |
| Maleic Acid SCHEMBL4301221 | 0.78 | ALDH1A1 (0.66) | KMT2ATAAR1ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20050256058-A1 | Propenoyl hydrazides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256058-A1 | Propenoyl hydrazides | DNPEP, HPN, PREP | LTB4R 3972/4885LTB4R2 4036/4885KMT2A 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.