Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023183 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4027112 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4777631 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4779451 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4021931 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4022602 | 0.81 | POLB (0.41) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4780139 | 0.81 | HRH3 (0.42) | ALDH1A1KMT2ALMNACYP2C19GAA | |
| SCHEMBL4021517 | 0.81 | HRH3 (0.42) | ALDH1A1KMT2ALMNACYP2C19GAA | |
| SCHEMBL4019459 | 0.80 | RORC (0.57) | ALDH1A1MAPTKMT2AKDM4ELMNA | |
| SCHEMBL4019955 | 0.80 | RORC (0.57) | ALDH1A1MAPTKMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | ALDH1A1 258/4885MAPT 3009/4885KMT2A 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.