Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.39 |
| ▸ | HTR3B | O95264 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 5/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123733 | 0.78 | UHRF1 (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10264975 | 0.71 | — | — | |
| SCHEMBL1703486 | 0.71 | PLG (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19879970 | 0.70 | — | — | |
| SCHEMBL13742411 | 0.67 | RECQL (0.44) | TRPA1RECQLLOXLOXL3LOXL2 | |
| SCHEMBL22263165 | 0.67 | ITGB3 (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Bromide SCHEMBL22263083 | 0.66 | ITGB3 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19879967 | 0.65 | TRPA1 (0.52) | TRPA1RECQLLOXLOXL3LOXL2 | |
| SCHEMBL3591519 | 0.65 | TRPA1 (0.56) | TRPA1RECQLLOXLOXL3LOXL2 | |
| SCHEMBL1191366 | 0.65 | TRPA1 (0.56) | TRPA1RECQLLOXLOXL3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |