SCHEMBL4022137

SCHEMBL4022137

O=S(=O)(O)CCCCN1CCN(CCCCS(=O)(=O)O)CC1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.42
PAOX Q6QHF9 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
KCNH2 Q12809 1/20 0.36
HTR4 Q13639 2/20 0.36
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
LMNA P02545 1/20 0.35
SLC6A6 P31641 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4016878 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4018181 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4020401 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4018976 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4014999 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4020106 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL4018698 0.98 PAOX (0.42) APPPAOXHRH3KCNH2HTR4
SCHEMBL671899 0.93 APP (0.44) APPPAOXHRH3PTGS1PDE4A
SCHEMBL118027 0.92 ALDH1A1 (0.45) APPPAOXHRH3KCNH2HTR4
SCHEMBL29023016 0.92 PAOX (0.52) APPPAOXHTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856748-B1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL UNIV CALIFORNIA (US) 2024-03-06 EP claimed
US-11850294-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2023-12-26 US claimed
US-20220079849-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2022-03-17 US claimed
EP-3468715-B1 A PROCESS FOR TREATING AN ALKYLATING CATALYST AND PRODUCING MONO-ALKYLATED AROMATIC COMPOUND EXXONMOBIL CHEMICAL PATENTS INC (US) 2026-04-01 EP disclosed
US-20240327442-A1 CONTROLLING METAL-ORGANIC FRAMEWORK MORPHOLOGY THROUGH COORDINATIVE MIMICRY ExxonMobil Technology and Engineering Company 2024-10-03 US disclosed
EP-4380944-A1 CONTROLLING METAL-ORGANIC FRAMEWORK MORPHOLOGY THROUGH COORDINATIVE MIMICRY The Regents of the University of California (US) 2024-06-12 EP disclosed
US-11986807-B2 Catalyst compositions and their use in aromatic alkylation processes ExxonMobil Engineering & Technology Company (US) 2024-05-21 US disclosed
EP-3600654-B1 METHODS FOR REMOVING IMPURITIES FROM A HYDROCARBON STREAM AND THEIR USE IN AROMATIC ALKYLATION PROCESSES EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-05-01 EP disclosed
US-11951463-B2 Catalyst compositions and their use in aromatic alkylation processes ExxonMobil Engineering & Technology Company (US) 2024-04-09 US disclosed
EP-3856748-B1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL UNIV CALIFORNIA (US) 2024-03-06 EP disclosed
CN-112771056-B Metal organic framework phase and crystallite shape control 加利福尼亚大学董事会 2024-02-23 CN disclosed
US-20200101439-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-04-02 US disclosed
WO-2020068996-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-02 WO disclosed
EP-2435531-B1 ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT SIEMENS AG (DE) 2013-10-30 EP disclosed
EP-1085540-B1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME SHOWA DENKO KK (JP) 2009-07-01 EP disclosed
US-6466421-B1 Solid electrolytic capacitor and method for producing the same SHOWA DENKO K.K. (JP) 2002-10-15 US disclosed
US-6344966-B1 ELECTRICALLY CONDUCTING POLYMER LAYER CONTAINS AS A DOPANT AN ANION OF(1) ALKOXY-SUBSTITUTED NAPHTHALENESULFONATE, (2) A HETEROCYCLIC SULFONATE, OR (3) AN ANION OF AN ALIPHATIC POLYCYCLIC COMPOUND SHOWA DENKO K.K. (JP) 2002-02-05 US disclosed
US-6281224-B1 BENZALKONIUM CHLORIDE EFFECTIVE AS A PRESERVATIVE, AND TROMETHAMINE EFFECTIVE TO KEEP THE SOLUTION STABLE AND CLEAR AND LOWERS EYE IRRITATION SANTEN PHARMACEUTICAL CO., LTD. (JP) 2001-08-28 US disclosed
EP-1085540-A1 SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME Showa Denko K K (JP) 2001-03-21 EP disclosed
EP-0824916-A1 PRANOPROFEN EYEDROPS CONTAINING ORGANIC AMINE SANTEN PHARMACEUTICAL CO., LTD. (JP) 1998-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11850294-B2 Buffered microencapsulated compositions and methods CHMP4B, LIPA, APOB APP 843/4885PAOX 1390/4885HRH3 3256/4885
US-20240327442-A1 CONTROLLING METAL-ORGANIC FRAMEWORK MORPHOLOGY THROUGH COORDINATIVE MIMICRY TPR, CA4, CA2 APP 4318/4885PAOX 197/4885HRH3 1577/4885
US-20220079849-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS CHMP4B, LIPA, APOB APP 843/4885PAOX 1390/4885HRH3 3256/4885
US-20200101439-A1 METAL-ORGANIC FRAMEWORK PHASE AND CRYSTALLITE SHAPE CONTROL POF1B, BMX, MB APP 4448/4885PAOX 1147/4885HRH3 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.