Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 7/20 | 0.35 |
| ▸ | MGLL | Q99685 | 9/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721155 | 1.00 | BCHE (0.36) | BCHEKIF11MGLLKCNH2HRH3 | |
| SCHEMBL4018821 | 1.00 | BCHE (0.36) | BCHEKIF11MGLLKCNH2HRH3 | |
| SCHEMBL4022425 | 0.95 | KIF11 (0.42) | BCHEKIF11MGLLKCNH2HRH3 | |
| SCHEMBL4020233 | 0.88 | HSD11B1 (0.39) | MGLL | |
| SCHEMBL13721388 | 0.88 | HSD11B1 (0.39) | MGLL | |
| SCHEMBL4020235 | 0.88 | HSD11B1 (0.39) | MGLL | |
| SCHEMBL4019114 | 0.86 | SIGMAR1 (0.38) | BCHEMGLLOPRD1OPRK1 | |
| SCHEMBL4019124 | 0.86 | SIGMAR1 (0.38) | BCHEMGLLOPRD1OPRK1 | |
| SCHEMBL4029041 | 0.86 | KDM4E (0.38) | BCHEMGLLOPRD1OPRK1 | |
| SCHEMBL4021758 | 0.86 | MGLL (0.36) | BCHEKIF11MGLLOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | BCHE 1682/4885KIF11 3745/4885MGLL 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.