Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197711 | 0.84 | RAB9A (0.46) | HDAC1 | |
| SCHEMBL3943593 | 0.81 | MAPT (0.39) | HDAC3HDAC1MTNR1AMTNR1BHTR2A | |
| SCHEMBL4204118 | 0.77 | HDAC1 (0.35) | HDAC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL4211554 | 0.77 | MAPT (0.50) | MTNR1AMTNR1BL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3941334 | 0.76 | MAPT (0.49) | HDAC3HDAC1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL3950925 | 0.75 | MAPT (0.51) | MTNR1AMTNR1BL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4038220 | 0.73 | ALDH1A1 (0.47) | MTNR1AMTNR1BL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3946900 | 0.73 | ALDH1A1 (0.49) | HDAC3HDAC1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL4023069 | 0.73 | MAPT (0.34) | MTNR1AMTNR1BL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3943591 | 0.72 | RAB9A (0.39) | HDAC3HDAC1MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |