SCHEMBL402387

SCHEMBL402387

Cc1ccc(Cl)cc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
TP53 P04637 1/20 0.63
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
MYC P01106 2/20 0.58
NR4A1 P22736 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
TSHR P16473 1/20 0.57
CASP1 P29466 1/20 0.57
KDM4E B2RXH2 2/20 0.55
HSD17B10 Q99714 1/20 0.55
NOTUM Q6P988 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
F7 P08709 1/20 0.47
F3 P13726 1/20 0.47
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10024286 0.85 SRD5A2 (0.55) ALDH1A1TP53CA1CA2MYC
SCHEMBL1502321 0.84 ALDH1A1 (0.48) ALDH1A1TP53CA1CA2MYC
SCHEMBL10024251 0.84 MCL1 (0.54) ALDH1A1TP53CA1CA2SMN1; SMN2
SCHEMBL109654 0.83 SMN1; SMN2 (0.63) ALDH1A1TP53CA1CA2MYC
SCHEMBL874097 0.83 ALDH1A1 (0.47) ALDH1A1TP53CA1CA2MYC
SCHEMBL3922668 0.83 ALDH1A1 (0.47) ALDH1A1TP53CA1CA2MYC
Hydrochloric Acid SCHEMBL14660084 0.81 SMN1; SMN2 (0.61) ALDH1A1TP53CA1CA2MYC
SCHEMBL1999332 0.81 ALDH1A1 (0.59) ALDH1A1TP53CA1CA2SMN1; SMN2
SCHEMBL28601069 0.80 ALDH1A1 (0.46) ALDH1A1TP53CA1CA2MYC
SCHEMBL17454062 0.80 PTGER1 (0.55) ALDH1A1TP53CA1CA2MYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
EP-3551634-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
WO-2018108231-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
CN-106748685-A A kind of method that parachlorotoluene continuous oxidation prepares 4-chloro-benzaldehyde 常州大学 2017-05-31 CN claimed
EP-2086963-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2015-09-16 EP claimed
CN-102399016-A Boiler water treatment agent PINQIAO ZHU 2012-04-04 CN claimed
US-7772180-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2010-08-10 US claimed
EP-2086963-A2 HEPATITIS C VIRUS INHIBITORS Brystol-Myers Squibb Company (US) 2009-08-12 EP claimed
WO-2008060927-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-05-22 WO claimed
US-20080119461-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2008-05-22 US claimed
US-4180679-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1979-12-25 US claimed
EP-4739668-A1 1,3-ISOINDOLINEDIONE DERIVATIVES AND HETEROAROMATIC ANALOGUES FOR STIMULATING ENDOTHELIAL CELL-PERICYTE INTERACTION Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) (NL) 2026-05-13 EP disclosed
CN-120248894-B Hydrogen peroxide etching solution for liquid crystal display panel and preparation method thereof 安瑞森(宿迁)电子材料有限公司 2026-03-17 CN disclosed
US-12565488-B2 Inhibitors of influenza virus replication COCRYSTAL PHARMA, INC. (US) 2026-03-03 US disclosed
US-4022801-A ANTIANXIETY AND ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1977-05-10 US disclosed
US-3947585-A ANTIANXIETY, ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1976-03-30 US disclosed
US-3935193-A ANTIBIOTICS TOYO JOZO KABUSHIKI KAISHA (JA) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119461-A1 Hepatitis C Virus Inhibitors HAVCR2, HCCS, PYGL ALDH1A1 623/4885TP53 1811/4885CA1 4242/4885
US-12565488-B2 Inhibitors of influenza virus replication IFNAR1, HCFC1, NR3C1 ALDH1A1 2260/4885TP53 2977/4885CA1 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.