Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MARS1 | P56192 | 5/20 | 0.48 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402387 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL28840070 | 0.84 | ALDH1A1 (0.55) | SRD5A2ALDH1A1TP53TSHRCASP1 | |
| SCHEMBL412559 | 0.83 | CA1 (0.71) | SRD5A2ALDH1A1TP53TSHRCASP1 | |
| SCHEMBL10024259 | 0.83 | MCL1 (0.56) | ALDH1A1EIF4EFABP4MCL1AKR1C2 | |
| SCHEMBL10024251 | 0.82 | MCL1 (0.54) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| SCHEMBL21857416 | 0.78 | TSHR (0.56) | SRD5A2ALDH1A1TP53TSHRCASP1 | |
| SCHEMBL28157812 | 0.78 | AHR (0.53) | SRD5A2TP53SMN1; SMN2MARS1NPC1 | |
| SCHEMBL10024258 | 0.78 | DCLRE1B (0.57) | NOTUMMCL1AKR1C2AKR1C1 | |
| SCHEMBL4602039 | 0.77 | TSHR (0.52) | SRD5A2ALDH1A1TP53TSHRCASP1 | |
| SCHEMBL70164 | 0.77 | MCL1 (0.66) | ALDH1A1MCL1AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | FAS SECURED CREDITORS HOLDCO, LLC | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | LCAT, DGAT2, SOAT2 | SRD5A2 712/4885ALDH1A1 1533/4885TP53 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.