Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028177 | 0.90 | CARM1 (0.35) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4028135 | 0.88 | — | — | |
| SCHEMBL4019728 | 0.86 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4027811 | 0.84 | KDM1A (0.34) | KDM1ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13721491 | 0.83 | KDM4E (0.34) | KDM4EMAPTPKMKDM1AHTR4 | |
| SCHEMBL4024718 | 0.83 | KDM4E (0.34) | KDM4EMAPTPKMKDM1AHTR4 | |
| SCHEMBL4021154 | 0.83 | KDM4E (0.34) | KDM4EMAPTPKMKDM1AHTR4 | |
| SCHEMBL4029054 | 0.83 | KDM2B (0.33) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4021684 | 0.81 | KDM2B (0.38) | CYP2C9 | |
| SCHEMBL4749430 | 0.80 | KIF11 (0.35) | KDM4ETAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |