Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 11/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 11/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029054 | 0.92 | KDM2B (0.33) | CARM1PRMT6TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4024780 | 0.90 | KDM4E (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4019728 | 0.89 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2HRH2HRH1 | |
| SCHEMBL4022484 | 0.85 | CARM1 (0.32) | CARM1PRMT6TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4027811 | 0.83 | KDM1A (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4029451 | 0.82 | CARM1 (0.37) | CARM1PRMT6PRMT8MGLLMEN1 | |
| SCHEMBL4027024 | 0.82 | HTR2A (0.35) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL4751580 | 0.82 | KIF11 (0.35) | TAS1R3TAS1R1TAS1R2HRH2HRH1 | |
| SCHEMBL4749430 | 0.82 | KIF11 (0.35) | TAS1R3TAS1R1TAS1R2HRH2HRH1 | |
| SCHEMBL4020351 | 0.82 | ESR1 (0.34) | CARM1PRMT6TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |