Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029168 | 0.93 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3950315 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL4204113 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4029459 | 0.80 | CCR5 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4023062 | 0.77 | MAPT (0.38) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL4199729 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL3945797 | 0.76 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3945800 | 0.76 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3265135 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4025967 | 0.75 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |