Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | MC4R | P32245 | 3/20 | 0.39 |
| ▸ | MC5R | P33032 | 3/20 | 0.39 |
| ▸ | MC3R | P41968 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029168 | 0.87 | ALDH1A1 (0.51) | NPC1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4025964 | 0.80 | ALDH1A1 (0.51) | NPC1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4204113 | 0.80 | ALDH1A1 (0.39) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL4029465 | 0.72 | RAB9A (0.51) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL4199729 | 0.72 | ALDH1A1 (0.41) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3265904 | 0.69 | RAB9A (0.58) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3942488 | 0.68 | RAB9A (0.49) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL3118257 | 0.68 | ADAM17 (0.54) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL4197711 | 0.67 | RAB9A (0.46) | RAB9ANPC1GABRA1GABRG2GABRB3 | |
| SCHEMBL4208314 | 0.67 | RAB9A (0.50) | RAB9ANPC1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |