Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950315 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1RAB9AHTR3E | |
| SCHEMBL4029168 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4025964 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4029459 | 0.80 | CCR5 (0.42) | ALDH1A1RAB9ANPC1GABRA1GABRB2 | |
| SCHEMBL3939700 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL4199729 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL3939702 | 0.73 | RAB9A (0.42) | ALDH1A1MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL4204118 | 0.71 | HDAC1 (0.35) | ALDH1A1MAPTL3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL4023062 | 0.70 | MAPT (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1558428 | 0.69 | PRKAB2 (0.50) | MAPTPRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |