Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018895 | 1.00 | PTGS2 (0.42) | PTGS2GAAOPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4018862 | 0.71 | SOS1 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL898940 | 0.69 | SLC6A2 (0.49) | PTGS2OPRM1SMN1; SMN2ALDH1A1SLC6A2 | |
| SCHEMBL898941 | 0.69 | SLC6A2 (0.49) | PTGS2OPRM1SMN1; SMN2ALDH1A1SLC6A2 | |
| SCHEMBL29170750 | 0.69 | HTR2A (0.41) | OPRM1SMN1; SMN2ALDH1A1HTR2ASLC6A2 | |
| SCHEMBL18497958 | 0.69 | GLB1 (0.35) | GAAALDH1A1SLC6A2SLC6A3SLC6A4 | |
| Tert-Butyl Formate SCHEMBL28055531 | 0.69 | OPRM1 (0.32) | OPRM1SLC6A2SLC6A3SLC6A4NR1I2 | |
| SCHEMBL6042929 | 0.68 | DRD2 (0.36) | HTR2ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14246861 | 0.68 | GBA1 (0.40) | OPRM1SMN1; SMN2ALDH1A1MAPTHTR2A | |
| SCHEMBL30875748 | 0.68 | SLC6A2 (0.62) | HTR2ASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092293-A1 | PYROLLIDINE-BASED COMPOUNDS | SHANGHAI TARGETDRUG CO., LTD. (CN) | 2009-07-30 | — | — | WO | disclosed |