Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032569 | 0.86 | ALDH1A1 (0.56) | KMT2APKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4028052 | 0.82 | MMP1 (0.52) | ALDH1A1MMP1MMP3MMP13MMP7 | |
| SCHEMBL14535952 | 0.78 | ALDH1A1 (0.60) | KMT2APKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4034942 | 0.77 | ALDH1A1 (0.55) | KMT2APKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1770227 | 0.74 | KMT2A (0.55) | KMT2APKMALDH1A1LMNAHTT | |
| SCHEMBL1770228 | 0.74 | KMT2A (0.55) | KMT2APKMALDH1A1LMNAHTT | |
| SCHEMBL1770230 | 0.74 | KMT2A (0.55) | KMT2APKMALDH1A1LMNAHTT | |
| SCHEMBL9082047 | 0.72 | ALDH1A1 (0.37) | KMT2APKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6480554 | 0.72 | ALDH1A1 (0.59) | KMT2APKMALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4031087 | 0.72 | ALDH1A1 (0.59) | KMT2APKMALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452527-B1 | AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION | SHISEIDO CO LTD (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7176217-B2 | Azabicyclo compound matrix metalloprotease inhibitor and skin preparation | SHISEIDO CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050009808-A1 | Azabicyclo compound matrix metalloprotease inibitor and skin preparation | SHISEIDO CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1452527-A1 | AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION | Shiseido Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009808-A1 | Azabicyclo compound matrix metalloprotease inibitor and skin preparation | MMP1, MMP16, MMP9 | KMT2A 927/4885PKM 4744/4885ALDH1A1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.