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Sugi Predict / Targets / MMP16

MMP16

Matrix metalloproteinase-16 · P51512 · MMP16 on Sugi Atlas →

8,248 patent compounds predicted against MMP16, 4,673 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL315035 SCHEMBL315035 0.77 13/20
SCHEMBL316169 SCHEMBL316169 0.77 13/20
SCHEMBL314397 SCHEMBL314397 0.79 12/20
SCHEMBL314725 SCHEMBL314725 0.74 12/20
SCHEMBL325258 SCHEMBL325258 0.67 12/20
SCHEMBL316301 SCHEMBL316301 0.79 11/20
SCHEMBL3534852 SCHEMBL3534852 0.77 11/20
SCHEMBL315452 SCHEMBL315452 0.67 11/20
SCHEMBL3534115 SCHEMBL3534115 0.67 11/20
SCHEMBL3534006 SCHEMBL3534006 0.66 11/20
SCHEMBL3537910 SCHEMBL3537910 0.63 11/20
SCHEMBL1021988 SCHEMBL1021988 0.63 11/20
SCHEMBL1022551 SCHEMBL1022551 0.58 11/20
SCHEMBL931939 SCHEMBL931939 0.57 11/20
SCHEMBL1022069 SCHEMBL1022069 0.57 11/20
SCHEMBL1023240 SCHEMBL1023240 0.56 11/20
SCHEMBL1022410 SCHEMBL1022410 0.54 11/20
SCHEMBL3536039 SCHEMBL3536039 0.67 10/20
SCHEMBL315453 SCHEMBL315453 0.64 10/20
SCHEMBL1020024 SCHEMBL1020024 0.66 9/20

Clinical trials — most relevant to MMP16 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY PHASE4SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM) PHASE4COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast PHASE2COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer PHASE1COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement PHASE1COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial nanCOMPLETED
Influence of Statins in Artery Aneurysms nanUNKNOWN
Cancer Fusion Hybrids and Desmoplasia nanUNKNOWN
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction nanCOMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects nanAVAILABLE
Matrix Metalloproteinase (MMP) in Heart Failure nanCOMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development nanCOMPLETED
Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital nanNOT_YET_RECRUITING
Periodontal Health in Post COVID-19 Patients nanUNKNOWN
Apoptotic Changes in Gingiva Caused by Smoking nanCOMPLETED
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels nanCOMPLETED
Plasma and Scarring of Diabetic Ulcers nanCOMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus nanCOMPLETED
Salivary Markers in Periodontal Disorders nanCOMPLETED
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis nanCOMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity nanWITHDRAWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease nanNOT_YET_RECRUITING
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma nanCOMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar nanCOMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence nanWITHDRAWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma nanUNKNOWN
Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering From Bullous Pemphigoid nanCOMPLETED
The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure nanCOMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9 nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP16 binder may also engage these)

ProteinNameSimilarity
Q9WTR0 — 1.000 Q9WTR0 →
O35548 — 1.000 O35548 →
O88766 — 0.997 O88766 →
MMP14 Matrix metalloproteinase-14 0.997 landscape →
Q28397 — 0.997 Q28397 →
P57748 — 0.996 P57748 →
Q10739 — 0.996 Q10739 →
Q95220 — 0.995 Q95220 →
P03957 — 0.995 P03957 →
P53690 — 0.995 P53690 →
G5EGM1 — 0.994 G5EGM1 →
A6H737 — 0.994 A6H737 →
Q9GLE4 — 0.993 Q9GLE4 →
Q9XSZ5 — 0.993 Q9XSZ5 →
P41246 — 0.993 P41246 →
Q5RES1 — 0.992 Q5RES1 →
O18927 — 0.992 O18927 →
Q9GKE1 — 0.992 Q9GKE1 →
Q08B63 — 0.992 Q08B63 →
MMP24 Matrix metalloproteinase-24 0.992 landscape →
Q9EPL5 — 0.992 Q9EPL5 →
Q94316 — 0.992 Q94316 →
P98060 — 0.992 P98060 →
Q921L8 — 0.992 Q921L8 →
Q6P6V1 — 0.991 Q6P6V1 →
P50280 — 0.991 P50280 →
O88923 — 0.991 O88923 →
O94910 — 0.991 O94910 →
P33435 — 0.991 P33435 →
P54631 — 0.990 P54631 →