Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019629 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4TSHRLOXSCN9A | |
| SCHEMBL4026490 | 0.98 | ALDH1A1 (0.34) | ALDH1A1CYP3A4TSHRLOXSCN9A | |
| SCHEMBL4025921 | 0.98 | ALDH1A1 (0.34) | ALDH1A1CYP3A4TSHRLOXSCN9A | |
| SCHEMBL4752900 | 0.92 | GYS1 (0.34) | GYS1 | |
| SCHEMBL4752899 | 0.92 | GYS1 (0.34) | GYS1 | |
| SCHEMBL4022158 | 0.88 | BCHE (0.31) | SCN9AKDM2B | |
| SCHEMBL4021872 | 0.88 | BCHE (0.31) | SCN9AKDM2B | |
| SCHEMBL4028067 | 0.86 | BCHE (0.30) | — | |
| SCHEMBL13721487 | 0.86 | OPRM1 (0.35) | KDM2B | |
| SCHEMBL4028041 | 0.86 | OPRM1 (0.35) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |