Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 9/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028007 | 0.85 | PTPN1 (0.47) | ALDH1A1KDM4EPOLBMAPTALOX15 | |
| SCHEMBL4028670 | 0.69 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL1034639 | 0.66 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHSD17B10TDP1 | |
| SCHEMBL4028669 | 0.65 | FEN1 (0.65) | ALDH1A1KDM4EPOLBMAPTHSD17B10 | |
| SCHEMBL4025292 | 0.62 | ERCC1 (0.48) | ALDH1A1KDM4EPOLBMAPTMAPK1 | |
| SCHEMBL420705 | 0.61 | KDM4E (0.55) | ALDH1A1KDM4EPOLBMAPTALOX15 | |
| SCHEMBL8937581 | 0.60 | KDM4E (0.44) | ALDH1A1KDM4EPOLBMAPTALOX15 | |
| SCHEMBL6092736 | 0.59 | LMNA (0.50) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8937617 | 0.59 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EPOLBMAPTALOX15 | |
| 4-Methylbenzoic Acid SCHEMBL27184809 | 0.58 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |