SCHEMBL8937581

SCHEMBL8937581

O=C(O)c1cc(-c2cccs2)n(O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
POLB P06746 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
PIM1 P11309 1/20 0.44
PIM3 Q86V86 1/20 0.44
PLK3 Q9H4B4 1/20 0.44
PIM2 Q9P1W9 1/20 0.44
SRPK1 Q96SB4 1/20 0.43
RPS6KB2 Q9UBS0 1/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MAOA P21397 2/20 0.40
APEX1 P27695 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8937617 0.79 SMN1; SMN2 (0.41) KDM4EPOLBALDH1A1MAPTHSD17B10
SCHEMBL27972287 0.70 EGLN1 (0.49) KDM4EMAPTEGLN1SRPK1RPS6KB2
SCHEMBL420705 0.68 KDM4E (0.55) KDM4EPOLBALDH1A1MAPTHSD17B10
SCHEMBL940399 0.68 KAT6A (0.57) KDM4EPOLBMAPTSRPK1RPS6KB2
SCHEMBL31222146 0.68 KAT6A (0.57) KDM4EPOLBMAPTSRPK1RPS6KB2
Benzoic Acid SCHEMBL26966093 0.67 DAO (0.54) KDM4EMAPTEGLN1KMT2ATDP1
SCHEMBL28656241 0.67 KAT6A (0.46) KDM4EMAPTEGLN1SRPK1RPS6KB2
SCHEMBL9019021 0.67 ALOX15 (0.48) ALOX15EGLN1KMT2AMEN1L3MBTL1
SCHEMBL16897065 0.66 MAOA (0.41) KDM4EPOLBALDH1A1MAPTHSD17B10
Benzoic Acid SCHEMBL23802630 0.66 KMT2A (0.43) KDM4EPOLBALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563166-A Thienyl- and furylpyrrole fungicidal agents AMERICAN CYANAMID CO. (US) 1996-10-08 US disclosed
US-5492925-A PROTECTING PLANTS AMERICAN CYANAMID COMPANY (US) 1996-02-20 US disclosed
US-5480902-A Thienylpyrrole fungicidal agents AMERICAN CYANAMID COMPANY (US) 1996-01-02 US disclosed
EP-0641794-A1 Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides AMERICAN CYANAMID COMPANY (US) 1995-03-08 EP disclosed