Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034573 | 0.84 | ERCC1 (0.57) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4028792 | 0.84 | ERCC1 (0.57) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4028040 | 0.83 | ERCC1 (0.45) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4028038 | 0.83 | ERCC1 (0.45) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4034538 | 0.82 | ERCC1 (0.35) | ERCC1FEN1ERCC4MAPTLMNA | |
| SCHEMBL4034683 | 0.80 | NPC1 (0.36) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4027681 | 0.79 | ERCC1 (0.41) | ERCC1FEN1ERCC4NPC1RAB9A | |
| SCHEMBL4026147 | 0.78 | FEN1 (0.39) | ERCC1FEN1ERCC4LMNASMN1; SMN2 | |
| SCHEMBL4028019 | 0.77 | FEN1 (0.39) | ERCC1FEN1ERCC4MAPK1 | |
| SCHEMBL4031565 | 0.76 | CXCR2 (0.39) | ERCC1FEN1ERCC4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |