Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034580 | 0.94 | LTB4R (0.39) | FEN1ERCC1ERCC4 | |
| SCHEMBL4029846 | 0.89 | FEN1 (0.36) | FEN1ERCC1ERCC4ALDH1A1CYP1A2 | |
| SCHEMBL4026142 | 0.84 | FEN1 (0.57) | FEN1ERCC1ERCC4P2RX3ALDH1A1 | |
| SCHEMBL4027681 | 0.79 | ERCC1 (0.41) | FEN1ERCC1ERCC4ALDH1A1PKM | |
| SCHEMBL4029257 | 0.79 | FEN1 (0.44) | FEN1ERCC1ERCC4ALDH1A1MAPK1 | |
| SCHEMBL4026962 | 0.79 | F2 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL4029150 | 0.78 | FEN1 (0.55) | FEN1ERCC1ERCC4 | |
| SCHEMBL4028795 | 0.78 | ERCC1 (0.39) | FEN1ERCC1ERCC4P2RX3ALDH1A1 | |
| SCHEMBL4031571 | 0.78 | ERCC1 (0.40) | FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL4028019 | 0.77 | FEN1 (0.39) | FEN1ERCC1ERCC4MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |