Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185276 | 0.94 | MAPT (0.61) | MAPTALDH1A1L3MBTL1KCNH3PPARG | |
| SCHEMBL4970157 | 0.79 | ALDH1A1 (0.89) | MAPTALDH1A1L3MBTL1KCNH3F2 | |
| SCHEMBL2065279 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1KCNH3DRD4 | |
| SCHEMBL6646246 | 0.79 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1KCNH3PPARG | |
| SCHEMBL5160329 | 0.79 | DRD4 (0.64) | MAPTALDH1A1L3MBTL1PPARGDRD2 | |
| SCHEMBL14968385 | 0.77 | ALDH1A1 (0.84) | MAPTALDH1A1L3MBTL1KCNH3F2 | |
| SCHEMBL11759173 | 0.77 | ALDH1A1 (0.84) | MAPTALDH1A1L3MBTL1KCNH3F2 | |
| SCHEMBL4104788 | 0.77 | ALDH1A1 (0.84) | MAPTALDH1A1L3MBTL1KCNH3F2 | |
| Hydrochloric Acid SCHEMBL3634998 | 0.77 | ALDH1A1 (0.94) | MAPTALDH1A1L3MBTL1KCNH3DRD4 | |
| SCHEMBL4643729 | 0.77 | ALDH1A1 (0.84) | MAPTALDH1A1L3MBTL1KCNH3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169593-A1 | METHOD OF USING AND PRODUCING TROPOELASTIN AND TROPOELASTIN BIOMATERIALS | BIOMEDICAL RESEARCH SERVICES, INC. (US) | 2009-07-02 | — | — | US | disclosed |