Tetradecane

Tetradecane

SCHEMBL4030208

CC(C)(N)O.CCCCCCCCCCCCCC.O=S(=O)(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Tetradecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
CA2 P00918 9/20 0.43
CA1 P00915 8/20 0.43
SMPD1 P17405 2/20 0.43
FDPS P14324 1/20 0.43
CES1 P23141 4/20 0.42
EPHX1 P07099 1/20 0.42
CA9 Q16790 6/20 0.41
CA12 O43570 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
PPARA Q07869 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9443895 0.84 SMPD1 (0.48) TP53CA2CA1SMPD1FDPS
Sulfuric Acid SCHEMBL25198201 0.84 SMPD1 (0.48) TP53CA2CA1SMPD1FDPS
Sulfuric Acid SCHEMBL9443894 0.84 SMPD1 (0.48) TP53CA2CA1SMPD1FDPS
Sulfuric Acid SCHEMBL25184770 0.84 SMPD1 (0.48) TP53CA2CA1SMPD1FDPS
Sulfuric Acid SCHEMBL9493020 0.84 SMPD1 (0.48) TP53CA2CA1SMPD1FDPS
Tetradecane SCHEMBL28202834 0.84 TP53 (0.58) TP53CA2CA1CA9CA12
Tetradecane SCHEMBL7611438 0.84 TP53 (0.58) TP53CA2CA1CA9CA12
Decane SCHEMBL13586006 0.84 TSHR (0.57) TP53CA2CA1CES1EPHX1
Dodecane SCHEMBL1939550 0.84 TSHR (0.57) TP53CA2CA1CES1EPHX1
Sulfuric Acid SCHEMBL1484174 0.84 TSHR (0.57) TP53CA2CA1CES1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070082033-A1 Substrate containing lipids BEIERSDORF AG (DE) 2007-04-12 US claimed
CN-113727697-B Hydrophilic silica/polymer blends 陶氏环球技术有限责任公司 2024-06-04 CN disclosed
US-11931447-B2 Polymer/hydrophilic silica oil blend DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-19 US disclosed
US-11771643-B2 Cleansing compositions completely based on bio-renewable sources GALAXY SURFACTANTS LTD. (IN) 2023-10-03 US disclosed
US-20230165784-A1 CLEANSING COMPOSITIONS COMPLETELY BASED ON BIO-RENEWABLE SOURCES GALAXY SURFACTANTS LTD. (IN) 2023-06-01 US disclosed
CN-115317408-A Transparent foaming bath oil with all-natural source and preparation method thereof 诺斯贝尔化妆品股份有限公司 2022-11-11 CN disclosed
US-20220160596-A1 HYDROPHILIC SILICA/POLYMER BLEND DOW GLOBAL TECHNOLOGIES LLC 2022-05-26 US disclosed
US-20220142903-A1 POLYMER/HYDROPHILIC SILICA OIL BLEND ROHM AND HAAS COMPANY 2022-05-12 US disclosed
CN-113727697-A Hydrophilic silica/polymer blends 陶氏环球技术有限责任公司 2021-11-30 CN disclosed
WO-2020223024-A1 HYDROPHILIC SILICA/POLYMER BLEND DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-05 WO disclosed
WO-2020223026-A1 POLYMER/HYDROPHILIC SILICA OIL BLEND DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-05 WO disclosed
EP-2082722-A2 Foaming self-warming cosmetic preparations Beiersdorf AG (DE) 2009-07-29 EP disclosed
US-20070082033-A1 Substrate containing lipids BEIERSDORF AG (DE) 2007-04-12 US disclosed
EP-0916334-A1 Detergent composition UNILEVER PLC (GB) 1999-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11931447-B2 Polymer/hydrophilic silica oil blend H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C9, MMS19 TP53 220/4885CA2 4246/4885CA1 1745/4885
US-20220160596-A1 HYDROPHILIC SILICA/POLYMER BLEND H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C9, CD44 TP53 339/4885CA2 3879/4885CA1 1890/4885
US-20070082033-A1 Substrate containing lipids LIPC, MGLL, LIPA TP53 4708/4885CA2 3806/4885CA1 3211/4885
US-20220142903-A1 POLYMER/HYDROPHILIC SILICA OIL BLEND H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C9, MMS19 TP53 220/4885CA2 4246/4885CA1 1745/4885
US-11771643-B2 Cleansing compositions completely based on bio-renewable sources PARG, PLIN3, PLK3 TP53 2951/4885CA2 3100/4885CA1 4783/4885
US-20230165784-A1 CLEANSING COMPOSITIONS COMPLETELY BASED ON BIO-RENEWABLE SOURCES PARG, PLIN3, PLK3 TP53 2951/4885CA2 3100/4885CA1 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.