Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22818518 | 0.92 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL24678777 | 0.92 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL30608530 | 0.92 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL15555233 | 0.92 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL16716775 | 0.92 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL8366250 | 0.90 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL5573680 | 0.90 | ALDH1A1 (0.50) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL18090495 | 0.89 | ALDH1A1 (0.41) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL12000717 | 0.88 | GAA (0.53) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL9240503 | 0.88 | TDP1 (0.42) | NPC1RAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217674-B1 | ELECTROACTIVE MATERIALS | DU PONT (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-8889269-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889269-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8652655-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8652655-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130193423-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130193423-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
| WO-2009067419-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | NPC1 587/4885RAB9A 2485/4885KDM4E 4501/4885 |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | NPC1 587/4885RAB9A 2485/4885KDM4E 4501/4885 |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | NPC1 587/4885RAB9A 2485/4885KDM4E 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.